Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 3/20 | 0.38 |
| ▸ | CLPP | Q16740 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570917 | 0.84 | AOX1 (0.44) | TACR3TACR2PARP1AOX1 | |
| SCHEMBL7564172 | 0.84 | TAS1R3 (0.41) | MEN1KMT2AL3MBTL1KDM4EMAPT | |
| SCHEMBL7566344 | 0.84 | HDAC1 (0.48) | MEN1KMT2ATACR3TACR2PARP1 | |
| SCHEMBL7567962 | 0.84 | TERT (0.39) | MEN1KMT2APARP1TAS1R3TAS1R1 | |
| SCHEMBL8414170 | 0.83 | AOX1 (0.42) | MEN1KMT2ATACR3CLPPTACR2 | |
| SCHEMBL7565911 | 0.83 | RAD52 (0.39) | MEN1KMT2ATACR3PARP1KDM4E | |
| SCHEMBL7571929 | 0.83 | TAS1R3 (0.48) | MEN1KMT2APARP1TAS1R3TAS1R1 | |
| SCHEMBL7567229 | 0.83 | TAS1R3 (0.37) | MEN1KMT2APARP1TAS1R3TAS1R1 | |
| SCHEMBL7567278 | 0.82 | AOX1 (0.38) | MEN1KMT2APARP1KDM4ETAS1R3 | |
| SCHEMBL7565944 | 0.81 | TAS1R3 (0.46) | MEN1KMT2ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |