Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 3/20 | 0.36 |
| ▸ | FOS | P01100 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441910 | 0.77 | BACE1 (0.62) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL6440618 | 0.77 | BACE1 (0.62) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL10335366 | 0.71 | — | — | |
| SCHEMBL14887095 | 0.68 | AKR1B1 (0.58) | BACE1AKR1B10AKR1B1GLO1 | |
| SCHEMBL6440499 | 0.66 | JUN (0.70) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL6440492 | 0.66 | JUN (0.70) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL16093483 | 0.64 | BACE1 (0.68) | BACE1GSK3BTLR9JUNFOS | |
| SCHEMBL514058 | 0.62 | KDM4E (0.64) | BACE1CYP3A4APPKDM4EHSD17B10 | |
| SCHEMBL514059 | 0.62 | KDM4E (0.64) | BACE1CYP3A4APPKDM4EHSD17B10 | |
| SCHEMBL12158684 | 0.62 | LMNA (0.53) | JUNKDM4EGAAMEN1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083614-A1 | NOVEL POLYHYDROXY CURCUMINS HAVING ANTIOXIDANT ACTIVITY | LAILA, IMPEX (IN) | 2002-10-24 | — | — | WO | disclosed |