Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897241 | 0.74 | THRB (0.47) | THRBALDH1A1TSHR | |
| SCHEMBL10027331 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MAPTTSHRELANEPOLB | |
| SCHEMBL10834615 | 0.74 | THRB (0.42) | THRBALDH1A1TSHR | |
| SCHEMBL28854186 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTELANEAPEX1HTT | |
| SCHEMBL10895269 | 0.74 | CYP2C19 (0.39) | THRBALDH1A1MAPTELANEPOLB | |
| SCHEMBL8957789 | 0.74 | ABCB11 (0.33) | ALDH1A1TSHRELANEPOLBAPEX1 | |
| SCHEMBL19327020 | 0.74 | ABCB11 (0.33) | ALDH1A1TSHRELANEPOLBAPEX1 | |
| SCHEMBL7622862 | 0.73 | KDM4E (0.37) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL11219958 | 0.73 | THRB (0.41) | THRBALDH1A1TSHR | |
| SCHEMBL9488997 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPTTSHRELANEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940694-B1 | Photochromic curable composition | TOKUYAMA CORP (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6194511-B1 | COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND | TOKUYAMA CORPORATION (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-0940694-A1 | Photochromic curable composition | TOKUYAMA CORPORATION (JP) | 1999-09-08 | — | — | EP | disclosed |