Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471918 | 0.84 | MGMT (0.37) | MGMTAPPBACE1MMP1MMP2 | |
| SCHEMBL141870 | 0.80 | LTA4H (0.50) | MGMTAPPBACE1 | |
| SCHEMBL251357 | 0.77 | MGMT (0.40) | MGMTMMP1MMP2MMP9MMP12 | |
| SCHEMBL9479303 | 0.75 | GAA (0.47) | — | |
| SCHEMBL2876554 | 0.75 | APP (0.33) | MGMTAPPBACE1MMP1MMP2 | |
| SCHEMBL8130697 | 0.75 | MAPT (0.43) | MGMTAPPBACE1 | |
| SCHEMBL8124374 | 0.75 | MAOA (0.43) | APPBACE1 | |
| SCHEMBL9682640 | 0.74 | MGMT (0.39) | MGMTMMP1MMP2MMP9MMP12 | |
| Hydrochloric Acid SCHEMBL27436301 | 0.73 | APP (0.32) | MGMTAPPBACE1 | |
| SCHEMBL7299255 | 0.73 | LTA4H (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |