Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525851 | 0.86 | TDP1 (0.32) | TDP1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL7568969 | 0.85 | PTPN1 (0.34) | TDP1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL12259683 | 0.84 | MEN1 (0.34) | TDP1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL7528138 | 0.82 | MEN1 (0.33) | TDP1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL7569354 | 0.80 | TDP1 (0.35) | TDP1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL12952370 | 0.80 | TDP1 (0.33) | TDP1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL6131956 | 0.80 | SLC2A1 (0.35) | TDP1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL11983659 | 0.79 | TDP1 (0.36) | TDP1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL7568918 | 0.79 | ALDH1A1 (0.40) | TDP1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL10106936 | 0.75 | SLC2A1 (0.36) | MEN1KMT2AMAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984929-B1 | NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THE SAME | CORNING SA (FR) | 2002-09-11 | — | — | EP | claimed |