Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 3/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417702 | 0.88 | TRPV4 (0.53) | P4HBMRGPRX4TRPV4XDHSLC22A12 | |
| SCHEMBL7561075 | 0.87 | KDM4E (0.47) | TAS2R14KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8612254 | 0.85 | TRPV4 (0.50) | P4HBMRGPRX4TRPV4PARP15PARP10 | |
| SCHEMBL2425056 | 0.78 | CES2 (0.47) | CYP3A4CYP2C9SLC9A1CYP2C19VNN1 | |
| SCHEMBL8805711 | 0.78 | PARP15 (0.46) | PARP15PARP10PARP2XDHSLC22A12 | |
| SCHEMBL23370123 | 0.76 | TRPV4 (0.50) | P4HBMRGPRX4TRPV4XDHSLC22A12 | |
| SCHEMBL2637596 | 0.76 | AR (0.53) | TAS2R14 | |
| SCHEMBL15855788 | 0.76 | CES2 (0.44) | P4HBMRGPRX4KDM4EALDH1A1HPGD | |
| SCHEMBL7026695 | 0.75 | CES2 (0.50) | P4HBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1787904 | 0.75 | AKR1C3 (0.56) | P4HBMRGPRX4TRPV4CYP2C9ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151534-A1 | Antithrombotic compounds | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151534-A1 | Antithrombotic compounds | SERPINC1, PF4, F2 | P4HB 1108/4885MRGPRX4 2050/4885TRPV4 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.