Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | FLT1 | P17948 | 1/20 | 0.60 |
| ▸ | FLT4 | P35916 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302754 | 0.89 | MAPT (0.61) | MAPTKMT2ATDP1RAB9ANPC1 | |
| SCHEMBL16174797 | 0.89 | MAPT (0.61) | MAPTKMT2ATDP1RAB9ANPC1 | |
| SCHEMBL4361418 | 0.87 | RORC (0.65) | MAPTKMT2ASMN1; SMN2GAAPOLB | |
| SCHEMBL16022508 | 0.86 | MAPT (0.50) | MAPTKMT2ATDP1RAB9ANPC1 | |
| SCHEMBL11676127 | 0.84 | KMT2A (0.69) | MAPTKMT2ATDP1RAB9ANPC1 | |
| SCHEMBL3099561 | 0.83 | RAB9A (0.62) | MAPTKMT2ATDP1RAB9ANPC1 | |
| SCHEMBL10126508 | 0.83 | NPC1 (0.67) | MAPTKMT2ATDP1RAB9ANPC1 | |
| SCHEMBL6971828 | 0.82 | FLT1 (0.57) | MAPTKMT2ATDP1RAB9ASMN1; SMN2 | |
| SCHEMBL3114410 | 0.82 | ALDH1A1 (0.55) | MAPTKMT2ATDP1RAB9ANPC1 | |
| SCHEMBL480106 | 0.81 | KMT2A (0.70) | MAPTKMT2ATDP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051033-B | Antiviral compound | 豪夫迈·罗氏有限公司 | 2018-02-16 | — | — | CN | disclosed |
| EP-2964633-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2017-04-19 | — | — | EP | disclosed |
| US-20170081312-A1 | ANTIVIRAL COMPOUNDS | HOFFMANN-LA ROCHE INC. | 2017-03-23 | — | — | US | disclosed |
| US-20170081312-A1 | ANTIVIRAL COMPOUNDS | HOFFMANN-LA ROCHE INC. | 2017-03-23 | — | — | US | disclosed |
| US-9540345-B2 | Antiviral compounds | HOFFMANN-LA ROCHE INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-9540345-B2 | Antiviral compounds | HOFFMANN-LA ROCHE INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-9487491-B2 | Diamino heterocyclic carboxamide compound | ASTELLAS PHARMA INC. (JP) | 2016-11-08 | — | — | US | disclosed |
| US-9487491-B2 | Diamino heterocyclic carboxamide compound | ASTELLAS PHARMA INC. (JP) | 2016-11-08 | — | — | US | disclosed |
| EP-2792674-B1 | IMIDAZOLIDINEDIONE COMPOUNDS AND THEIR USES | HINOVA PHARMACEUTICAL INC (CN) | 2016-05-25 | — | — | EP | disclosed |
| US-9346764-B2 | Imidazolidinedione compounds and their uses | HINOVA PHARMACEUTICALS INC. (CN) | 2016-05-24 | — | — | US | disclosed |
| US-20140371284-A1 | IMIDAZOLIDINEDIONE COMPOUNDS AND THEIR USES | HC PHARMACEUTICAL CO., LTD. (CN) | 2014-12-18 | — | — | US | disclosed |
| US-20140371284-A1 | IMIDAZOLIDINEDIONE COMPOUNDS AND THEIR USES | HC PHARMACEUTICAL CO., LTD. (CN) | 2014-12-18 | — | — | US | disclosed |
| US-20140371284-A1 | IMIDAZOLIDINEDIONE COMPOUNDS AND THEIR USES | HC PHARMACEUTICAL CO., LTD. (CN) | 2014-12-18 | — | — | US | disclosed |
| US-20140371196-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-18 | — | — | US | disclosed |
| US-20140371196-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-18 | — | — | US | disclosed |
| EP-2792674-A1 | IMIDAZOLIDINEDIONE COMPOUNDS AND THEIR USES | HC Pharmaceutical Co., Ltd. (CN) | 2014-10-22 | — | — | EP | disclosed |
| WO-2014135471-A1 | ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-09-12 | — | — | WO | disclosed |
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-16 | — | — | US | disclosed |
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | WATERS TECHNOLOGIES CORPORATION (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081312-A1 | ANTIVIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | MAPT 4501/4885KMT2A 4621/4885TDP1 2908/4885 |
| US-20140371196-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | MAPT 3116/4885KMT2A 103/4885TDP1 2738/4885 |
| US-20120040968-A1 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | EML4, ALK, ERBB4 | MAPT 3116/4885KMT2A 103/4885TDP1 2738/4885 |
| US-20140371284-A1 | IMIDAZOLIDINEDIONE COMPOUNDS AND THEIR USES | AR, CYP19A1, CYP17A1 | MAPT 3666/4885KMT2A 3275/4885TDP1 3220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.