Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412284 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDLMNA | |
| SCHEMBL1547992 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDLMNA | |
| SCHEMBL8637991 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDLMNA | |
| SCHEMBL10731279 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDLMNA | |
| SCHEMBL74371 | 0.89 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDLMNA | |
| SCHEMBL10731267 | 0.86 | ALDH1A1 (0.56) | ALDH1A1ATMTSHRHPGDLMNA | |
| Butanedione SCHEMBL2230282 | 0.83 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDLMNA | |
| SCHEMBL370998 | 0.82 | NAAA (0.56) | ALDH1A1ATMTSHRLMNAMAPK1 | |
| SCHEMBL30525457 | 0.82 | NAAA (0.56) | ALDH1A1ATMTSHRLMNAMAPK1 | |
| SCHEMBL7567442 | 0.82 | HCAR2 (0.39) | ALDH1A1ATMTSHRLMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976738-B1 | Process for the preparation of propylene ureas | DAINIPPON INK & CHEMICALS (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6348594-B2 | HARDENING OF POLYMERS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-02-19 | — | — | US | disclosed |
| US-20020004599-A1 | PROPYLENE UREAS AND PROCESS FOR THEIR PREPARATION. | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-01-10 | — | — | US | disclosed |
| EP-0863131-B1 | Acrylic monomers, polymers thereof and crosslinking compositions | DAINIPPON INK & CHEMICALS (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0976738-A2 | Propylene ureas and the process for their preparation | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-02-02 | — | — | EP | disclosed |
| EP-0863131-A1 | Acrylic monomers, polymers thereof and crosslinking compositions | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-09-09 | — | — | EP | disclosed |
| EP-0599198-A1 | Process for the preparation of 5-arylhydantoins | Chemie Linz GmbH (AT) | 1994-06-01 | — | — | EP | disclosed |
| US-4770668-A | FOR CELLULOSE FABRICS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1988-09-13 | — | — | US | disclosed |
| US-4584387-A | INTERMEDIATES FOR ALPHA-HYDROXY ALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0050351-B1 | OPTICALLY ACTIVE OR RACEMIC ALPHA-HYDROXYALDEHYDES AND BENZYL DERIVATIVES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-03-27 | — | — | EP | disclosed |
| EP-0048501-B1 | OPTICALLY ACTIVE OR RACEMIC DIAZABICYCLOOCTANE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-07-27 | — | — | EP | disclosed |
| US-4383122-A | HYDROCARBOYL-1,3-DIAZABICYCLO(3.3.0)OCTANE, GRIGNARD REAGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0011417-B1 | OPTICALLY ACTIVE OR RACEMIC AMINAL DERIVATIVES, PROCESS FOR PREPARING SAME AND FOR CONVERTING SAME TO ALPHA-HYDROXYALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-04 | — | — | EP | disclosed |
| US-4337346-A | CONDENSATION OF A GLYOXAL WITH AN N-SUBSTITUTED AMINOMETHYLPYRROLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0050351-A1 | Optically active or racemic alpha-hydroxyaldehydes and benzyl derivatives thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-28 | — | — | EP | disclosed |
| EP-0048501-A1 | Optically active or racemic diazabicyclooctane derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-31 | — | — | EP | disclosed |
| EP-0011417-A1 | Optically active or racemic aminal derivatives, process for preparing same and for converting same to alpha-hydroxyaldehydes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004599-A1 | PROPYLENE UREAS AND PROCESS FOR THEIR PREPARATION. | UQCRB, URB2, ADH1C | ALDH1A1 1778/4885ATM 1554/4885TSHR 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.