Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414229 | 0.87 | HCAR2 (0.43) | HCAR2ALDH1A1LMNATDP1ESR1 | |
| SCHEMBL14672059 | 0.87 | HCAR2 (0.43) | HCAR2ALDH1A1LMNATDP1ESR1 | |
| SCHEMBL8636453 | 0.87 | HCAR2 (0.43) | HCAR2ALDH1A1LMNATDP1ESR1 | |
| SCHEMBL2866836 | 0.87 | HCAR2 (0.43) | HCAR2ALDH1A1LMNATDP1ESR1 | |
| Ammonia Solution, Strong SCHEMBL21219091 | 0.85 | HCAR2 (0.41) | HCAR2ALDH1A1LMNATDP1ESR1 | |
| SCHEMBL6990282 | 0.83 | NAAA (0.35) | HCAR2ALDH1A1LMNATDP1ESR1 | |
| SCHEMBL7566937 | 0.82 | ALDH1A1 (0.52) | HCAR2ALDH1A1LMNATDP1ESR1 | |
| SCHEMBL2859729 | 0.79 | TSHR (0.46) | HCAR2ALDH1A1LMNATDP1ESR1 | |
| SCHEMBL6496148 | 0.78 | HCAR2 (0.40) | HCAR2ALDH1A1LMNATDP1ESR1 | |
| SCHEMBL10625346 | 0.78 | TSHR (0.39) | ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976738-B1 | Process for the preparation of propylene ureas | DAINIPPON INK & CHEMICALS (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6348594-B2 | HARDENING OF POLYMERS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-02-19 | — | — | US | disclosed |
| US-20020004599-A1 | PROPYLENE UREAS AND PROCESS FOR THEIR PREPARATION. | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-01-10 | — | — | US | disclosed |
| EP-0976738-A2 | Propylene ureas and the process for their preparation | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-02-02 | — | — | EP | disclosed |
| EP-0599198-A1 | Process for the preparation of 5-arylhydantoins | Chemie Linz GmbH (AT) | 1994-06-01 | — | — | EP | disclosed |
| US-4584387-A | INTERMEDIATES FOR ALPHA-HYDROXY ALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0050351-B1 | OPTICALLY ACTIVE OR RACEMIC ALPHA-HYDROXYALDEHYDES AND BENZYL DERIVATIVES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-03-27 | — | — | EP | disclosed |
| EP-0048501-B1 | OPTICALLY ACTIVE OR RACEMIC DIAZABICYCLOOCTANE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-07-27 | — | — | EP | disclosed |
| US-4383122-A | HYDROCARBOYL-1,3-DIAZABICYCLO(3.3.0)OCTANE, GRIGNARD REAGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0011417-B1 | OPTICALLY ACTIVE OR RACEMIC AMINAL DERIVATIVES, PROCESS FOR PREPARING SAME AND FOR CONVERTING SAME TO ALPHA-HYDROXYALDEHYDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-04 | — | — | EP | disclosed |
| US-4337346-A | CONDENSATION OF A GLYOXAL WITH AN N-SUBSTITUTED AMINOMETHYLPYRROLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0050351-A1 | Optically active or racemic alpha-hydroxyaldehydes and benzyl derivatives thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-28 | — | — | EP | disclosed |
| EP-0048501-A1 | Optically active or racemic diazabicyclooctane derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-31 | — | — | EP | disclosed |
| EP-0011417-A1 | Optically active or racemic aminal derivatives, process for preparing same and for converting same to alpha-hydroxyaldehydes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004599-A1 | PROPYLENE UREAS AND PROCESS FOR THEIR PREPARATION. | UQCRB, URB2, ADH1C | HCAR2 2685/4885ALDH1A1 1778/4885LMNA 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.