SCHEMBL756755

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27861788	0.89	ALDH1A1 (0.46)	ALDH1A1NPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL754228	0.81	LIPG (0.42)	ALDH1A1NPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL754495	0.81	KMT2A (0.39)	ALDH1A1NPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL754494	0.81	KMT2A (0.39)	ALDH1A1NPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL753309	0.79	CNR2 (0.40)	L3MBTL1CNR1POLB
	SCHEMBL27861541	0.76	ALDH1A1 (0.35)	ALDH1A1NPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL27606139	0.76	ALDH1A1 (0.35)	ALDH1A1NPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL755219	0.74	CNR2 (0.44)	ALDH1A1NPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL755038	0.73	POLB (0.40)	ALDH1A1NPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL751257	0.72	MTNR1A (0.38)	KMT2ACNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.