SCHEMBL754228

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754205	0.82	LIPG (0.47)	LIPGHSP90AA1RXFP1LIPC
	SCHEMBL752850	0.82	LIPG (0.47)	LIPGHSP90AA1LIPC
	SCHEMBL755310	0.81	LIPG (0.43)	LIPGHSP90AA1LIPC
	SCHEMBL27861788	0.81	ALDH1A1 (0.46)	ALDH1A1NPC1TSHRKMT2AMEN1
	SCHEMBL756755	0.81	ALDH1A1 (0.47)	ALDH1A1NPC1TSHRKMT2AMEN1
	SCHEMBL754111	0.80	LIPG (0.45)	LIPGKMT2AMEN1HSP90AA1LIPC
	SCHEMBL764369	0.79	LIPG (0.33)	LIPGTSHRHSP90AA1
	SCHEMBL753861	0.77	LIPG (0.43)	LIPGALDH1A1HSP90AA1RXFP1LIPC
	SCHEMBL753687	0.77	LIPG (0.43)	LIPGLIPC
	SCHEMBL754083	0.77	LIPG (0.45)	LIPGHSP90AA1LIPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.