Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6769742 | 0.99 | ALDH1A1 (0.42) | ALDH1A1KMT2ALMNAGABRA1GABRG2 | |
| SCHEMBL7499586 | 0.77 | SIRT6 (0.45) | ALDH1A1KMT2ALMNAMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL6765057 | 0.76 | SIRT6 (0.44) | ALDH1A1KMT2ALMNAMAPTNPC1 | |
| SCHEMBL2625723 | 0.71 | CCNT1 (0.51) | ALDH1A1KMT2ALMNAGABRA1GABRG2 | |
| SCHEMBL10036370 | 0.69 | SLC6A4 (0.62) | ALDH1A1KMT2ALMNA | |
| SCHEMBL30736527 | 0.69 | SLC6A4 (0.62) | ALDH1A1KMT2ALMNA | |
| SCHEMBL4005594 | 0.69 | LMNA (0.47) | ALDH1A1KMT2ALMNAGABRA1GABRG2 | |
| SCHEMBL31463527 | 0.69 | MAPT (0.43) | ALDH1A1KMT2ALMNAGABRA1GABRG2 | |
| SCHEMBL10822491 | 0.68 | CASP6 (0.52) | ALDH1A1KMT2ALMNAGABRA1GABRG2 | |
| SCHEMBL9080670 | 0.68 | MAPT (0.43) | ALDH1A1KMT2ALMNAGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1390206-A | Inhibitors of factor Xa | COR THERAPEUTICS INC (US) | 2003-01-08 | — | — | CN | disclosed |
| EP-1216231-A2 | INHIBITORS OF FACTOR Xa | Millennium Pharmaceuticals, Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019798-A2 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC. (US) | 2001-03-22 | — | — | WO | disclosed |