Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 4/20 | 0.41 |
| ▸ | ACACA | Q13085 | 3/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561981 | 0.90 | SMN1; SMN2 (0.47) | MMP12MMP13ACACBACACANPY5R | |
| SCHEMBL7561017 | 0.90 | SMN1; SMN2 (0.45) | ALDH1A1MMP12MMP13HTTSMN1; SMN2 | |
| SCHEMBL7561001 | 0.89 | MMP13 (0.39) | ALDH1A1MMP12MMP13ACACBACACA | |
| SCHEMBL7561006 | 0.84 | SMN1; SMN2 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL7567148 | 0.80 | NPC1 (0.38) | ALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL7563408 | 0.79 | NPSR1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7563430 | 0.78 | LMNA (0.48) | MEN1HTTKMT2ASMN1; SMN2HPGD | |
| SCHEMBL7568124 | 0.77 | MMP12 (0.48) | ALDH1A1MMP12MMP13ACACBACACA | |
| SCHEMBL7562938 | 0.77 | MMP12 (0.48) | ALDH1A1MMP12MMP13ACACBACACA | |
| SCHEMBL7570062 | 0.76 | MMP12 (0.45) | MMP12MMP13ACACBACACANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882703-B1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6011174-A | INHIBIT PROTEIN-FARNESYL TRANSFERASE (PFT) IN VIVO THEREBY TO SUPPRESS FUNCTION OF ONCOGENE PROTEIN RAS AND THUS PRESENT ANTITUMOR ACTIVITIES, | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0882703-A1 | CYCLIC AMIC ACID DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |