Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488434 | 0.87 | ADRA2B (0.44) | PPARGPPARAALDH1A1ADRA2BADRA2C | |
| SCHEMBL142479 | 0.87 | ADRA2B (0.44) | PPARGPPARAALDH1A1ADRA2BADRA2C | |
| SCHEMBL1446062 | 0.86 | LIPG (0.47) | ALDH1A1TSHRLIPG | |
| SCHEMBL8733147 | 0.85 | ADRA2B (0.39) | PPARGPPARAALDH1A1TSHRADRA2B | |
| SCHEMBL7415136 | 0.84 | LIPG (0.55) | PPARGPPARALIPG | |
| Ammonia Solution, Strong SCHEMBL2913066 | 0.84 | LIPG (0.46) | ALDH1A1TSHRLIPG | |
| Benzene SCHEMBL11786397 | 0.84 | KDM4E (0.44) | PPARGPPARAALDH1A1ADRA2BADRA2C | |
| SCHEMBL9839840 | 0.84 | ADRA2B (0.43) | PPARGPPARAALDH1A1ADRA2BADRA2C | |
| SCHEMBL10608856 | 0.82 | LIPG (0.58) | PPARGPPARATSHRLIPG | |
| SCHEMBL11780518 | 0.82 | LIPG (0.58) | PPARGPPARATSHRLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| EP-0637580-B1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-1140930-A1 | DIBENZO a,g]QUINOLIZINIUM DERIVATIVES AND THE SALTS THEREOF | HANWHA CHEMICAL CORPORATION (KR) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037468-A1 | DIBENZO[a,g]QUINOLIZINIUM DERIVATIVES AND THE SALTS THEREOF | HANWHA CHEMICAL CORPORATION (KR) | 2000-06-29 | — | — | WO | disclosed |
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |
| EP-0428081-B1 | Method for producing diarylmethanes | KUREHA CHEMICAL IND CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5068481-A | Reaction of benzyl chloride with benzene or alkylbenzene in the presence of a zeolite catalyst | KUREHA KAGAKU KOGYO K.K. (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0428081-A1 | Method for producing diarylmethanes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-5003123-A | Process for the preparation of cyclobutenoarenes | SHELL OIL COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0182872-B1 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS | THE DOW CHEMICAL COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0182872-A4 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS. | DOW CHEMICAL CO (US) | 1986-08-21 | — | — | EP | disclosed |
| EP-0182872-A1 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS. | DOW CHEMICAL CO (US) | 1986-06-04 | — | — | EP | disclosed |
| US-4570011-A | PYROLYSIS OF AN ORTHO ALKYL HALOMETHYL AROMATIC HYDROCARBON IN AN INERT | THE DOW CHEMICAL COMPANY (US) | 1986-02-11 | — | — | US | disclosed |
| WO-1985005355-A1 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS | THE DOW CHEMICAL COMPANY (US) | 1985-12-05 | — | — | WO | disclosed |
| US-4237016-A | NONIONIC SOFTENING AGENT AND A POLYMERIC CATIONIC SALT | THE PROCTER & GAMBLE COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| EP-0002085-A2 | Textile conditioning compositions with low content of cationic guar gum | THE PROCTER & GAMBLE COMPANY (US) | 1979-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | PPARG 1107/4885PPARA 1304/4885ALDH1A1 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.