Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254714 | 0.91 | KDM1A (0.47) | KDM1AMAOAMAOBGAARAB9A | |
| SCHEMBL6258048 | 0.91 | KDM1A (0.47) | KDM1AMAOAMAOBGAARAB9A | |
| Hydrochloric Acid SCHEMBL7564142 | 0.90 | KDM1A (0.49) | KDM1AMAOAMAOBGAARAB9A | |
| SCHEMBL7110629 | 0.79 | ALDH1A1 (0.40) | KDM1AMAOAMAOBRAB9ASMN1; SMN2 | |
| SCHEMBL7109309 | 0.78 | KDM1A (0.38) | KDM1AMAOAMAOBRAB9ASMN1; SMN2 | |
| SCHEMBL10271980 | 0.74 | KDM1A (0.44) | KDM1AMAOAMAOBGAARAB9A | |
| SCHEMBL6257456 | 0.73 | TAAR1 (0.47) | KDM1AMAOAMAOBTSHRALDH1A1 | |
| SCHEMBL7569169 | 0.73 | RAB9A (0.38) | KDM1AMAOAMAOBGAAPOLB | |
| SCHEMBL10340138 | 0.72 | KMT2A (0.37) | RAB9AGABRA1SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7561980 | 0.72 | NOS2 (0.46) | KDM1AMAOAMAOBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420566-B2 | NITRIC OXIDE SYNTHASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2002-07-16 | — | — | US | disclosed |
| US-20020019427-A1 | Pharmaceutical compositions containing a 4, 5-dihydro-1, 3-thiazol-2-ylamine derivative, novel derivatives and preparation thereof | AVENTIS PHARMA S.A. (FR) | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019427-A1 | Pharmaceutical compositions containing a 4, 5-dihydro-1, 3-thiazol-2-ylamine derivative, novel derivatives and preparation thereof | ALK, QDPR, CYP3A7 | KDM1A 1799/4885MAOA 667/4885MAOB 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.