Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.39 |
| ▸ | AGT | P01019 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709729 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2AGT | |
| SCHEMBL7567246 | 0.74 | RXRA (0.44) | AGTR1AGTR2MAP4K4 | |
| SCHEMBL9093218 | 0.73 | AGTR1 (0.48) | AGTR1AGTR2AGTALDH1A1MEN1 | |
| SCHEMBL3061585 | 0.73 | AGTR1 (0.44) | AGTR1AGTR2AGTMEN1KMT2A | |
| SCHEMBL30316147 | 0.72 | AGTR1 (0.51) | AGTR1AGTR2AGTHDAC6MKNK2 | |
| SCHEMBL9024777 | 0.72 | AGTR1 (0.51) | AGTR1AGTR2AGTHDAC6MKNK2 | |
| SCHEMBL9591953 | 0.72 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL4246354 | 0.71 | AGTR1 (0.50) | AGTR1AGTR2AGTL3MBTL1POLB | |
| SCHEMBL9709679 | 0.71 | CD38 (0.45) | AGTR1AGTR2AGTMEN1KMT2A | |
| SCHEMBL9709873 | 0.71 | AGTR1 (0.45) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685470-B1 | Benzene derivatives and pharmaceutical composition | KUREHA CHEMICAL IND CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |