Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042982 | 0.74 | SLC6A2 (0.46) | SLC6A3SLC6A2SLC6A4MCHR1KCNH2 | |
| SCHEMBL7110058 | 0.72 | RAB9A (0.36) | KDM4EGAAMAPTLMNA | |
| SCHEMBL8492856 | 0.69 | EPHX1 (0.48) | ALDH1A1GAALMNAKMT2A | |
| SCHEMBL11363300 | 0.68 | L3MBTL1 (0.49) | SLC6A3MEN1LMNAKMT2ACYP2D6 | |
| SCHEMBL6042548 | 0.68 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6044044 | 0.68 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6042543 | 0.68 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5010541 | 0.67 | ALDH1A1 (0.51) | KDM4EALDH1A1GAAHTT | |
| SCHEMBL6043121 | 0.66 | CASR (0.47) | ALDH1A1GAAMCHR1 | |
| SCHEMBL10120468 | 0.65 | UGT2B7 (0.55) | MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |