Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564869 | 0.93 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3ALOX15 | |
| SCHEMBL7569676 | 0.87 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3ALOX15 | |
| SCHEMBL7564855 | 0.87 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNB4CHRNA3ALOX15 | |
| SCHEMBL11257974 | 0.82 | CA2 (0.50) | TSHRPRKCAPRKCDCA1CA2 | |
| SCHEMBL15360245 | 0.82 | CA2 (0.50) | TSHRPRKCAPRKCDCA1CA2 | |
| SCHEMBL23187892 | 0.81 | CTSK (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3ALOX15 | |
| SCHEMBL3647097 | 0.81 | PRKCA (0.44) | PRKCAPRKCDCA1CA2CTSK | |
| SCHEMBL7563877 | 0.81 | NAAA (0.42) | CHRNB2CHRNA4CHRNB4CHRNA3TSHR | |
| SCHEMBL7570273 | 0.81 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3ALOX15 | |
| SCHEMBL30746068 | 0.79 | PRKCA (0.43) | LMNAPRKCAPRKCDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855393-B1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KK (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-5922882-A | ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-07-13 | — | — | US | disclosed |
| EP-0855393-A1 | BISBENZOTRIAZOLYLPHENOLS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-07-29 | — | — | EP | disclosed |