Sugi Predict

Sugi Predict / Compounds / SCHEMBL757032

SCHEMBL757032

SCHEMBL757032

CN(C)C(On1nnc2ccccc2c1=O)N(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.51
▸ SMN1; SMN2 Q16637 5/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ NPC1 O15118 5/20 0.42
▸ RAB9A P51151 5/20 0.42
▸ HPSE Q9Y251 1/20 0.41
▸ LMNA P02545 3/20 0.40
▸ ALOX15 P16050 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ HPGD P15428 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12735284 0.83 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1
SCHEMBL757273 0.78 TSHR (0.49) ALDH1A1SMN1; SMN2CYP1A2KMT2ANPC1
SCHEMBL757021 0.78 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1
SCHEMBL5651138 0.75 HPSE (0.50) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1
SCHEMBL22109793 0.75 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1
SCHEMBL24437289 0.74 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1
SCHEMBL10284047 0.74 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1
SCHEMBL10098857 0.73 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1
SCHEMBL4012048 0.73 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1
SCHEMBL1561845 0.73 HPSE (0.53) ALDH1A1SMN1; SMN2CYP1A2CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9487592-B2 Immobilization substrate and method for producing the same FUJIFILM CORPORATION (JP) 2016-11-08 — — US disclosed
US-9487592-B2 Immobilization substrate and method for producing the same FUJIFILM CORPORATION (JP) 2016-11-08 — — US disclosed
US-20150024392-A1 METHOD FOR PRODUCING A BIOSENSOR FUJIFILM CORPORATION (JP) 2015-01-22 — — US disclosed
US-20150024392-A1 METHOD FOR PRODUCING A BIOSENSOR FUJIFILM CORPORATION (JP) 2015-01-22 — — US disclosed
US-8839961-B2 Method for producing a biosensor FUJIFILM CORPORATION (JP) 2014-09-23 — — US disclosed
US-8839961-B2 Method for producing a biosensor FUJIFILM CORPORATION (JP) 2014-09-23 — — US disclosed
US-8557194-B2 Carrier, process for producing same, bioreactor, and chip for surface plasmon resonance analysis FUJIFILM CORPORATION (JP) 2013-10-15 — — US disclosed
US-8236575-B2 Carrier for analysis of an analyte and process for producing the same FUJIFILM CORPORATION (JP) 2012-08-07 — — US disclosed
US-8137733-B2 Process for producing a carrier FUJIFILM CORPORATION (JP) 2012-03-20 — — US disclosed
US-20110274846-A1 CARRIER, PROCESS FOR PRODUCING SAME, BIOREACTOR, AND CHIP FOR SURFACE PLASMON RESONANCE ANALYSIS FUJIFILM CORPORATION (JP) 2011-11-10 — — US disclosed
US-20090140209-A1 PROCESS FOR PRODUCING A CARRIER FUJIFILM CORPORATION (JP) 2009-06-04 — — US disclosed
US-20090081427-A1 METHOD FOR PRODUCING AN IMMOBILIZATION SUBSTRATE AND IMMOBILIZATION SUBSTRATE PRODUCED BY THE METHOD FUJIFILM CORPORATION (JP) 2009-03-26 — — US disclosed
US-20090062515-A1 METHOD FOR PURIFYING BIOACTIVE SUBSTANCES FUJIFILM CORPORATION (JP) 2009-03-05 — — US disclosed
US-20090016933-A1 CARRIER, PROCESS FOR PRODUCING SAME, BIOREACTOR, AND CHIP FOR SURFACE PLASMON RESONANCE ANALYSIS FUJIFILM CORPORATION (JP) 2009-01-15 — — US disclosed
US-20080187462-A1 PHYSIOLOGICALLY ACTIVE SUBSTANCE-IMMOBILIZED SUBSTRATE FUJIFILM CORPORATION (JP) 2008-08-07 — — US disclosed
US-20080187977-A1 METHOD FOR PRODUCTION OF PHYSIOLOGICALLY ACTIVE SUBSTANCE-IMMOBILIZED SUBSTRATE FUJIFILM CORPORATION (JP) 2008-08-07 — — US disclosed
US-20080188010-A1 Non-specific adsorption on oxide films FUJIFILM CORPORATION (JP) 2008-08-07 — — US disclosed
US-20080090306-A1 METHOD FOR IMMOBILIZING BIOMOLECULES FUJIFILM CORPORATION (JP) 2008-04-17 — — US disclosed
US-20070258866-A1 Method for producing a biosensor FUJIFILM CORPORATION 2007-11-08 — — US disclosed
US-20070258866-A1 Method for producing a biosensor FUJIFILM CORPORATION 2007-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062515-A1 METHOD FOR PURIFYING BIOACTIVE SUBSTANCES BMP2, BMP1, BMP4 ALDH1A1 1572/4885SMN1; SMN2 4640/4885CYP1A2 3800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.