SCHEMBL4012048

SCHEMBL4012048

CS(=O)(=O)On1nnc2ccccc2c1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
MAPT P10636 3/20 0.44
HPSE Q9Y251 1/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14620595 0.85 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KMT2A
SCHEMBL11450683 0.82 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KMT2A
SCHEMBL757021 0.80 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KMT2A
SCHEMBL14620598 0.79 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KMT2A
SCHEMBL958454 0.79 TSHR (0.50) ALDH1A1SMN1; SMN2CYP1A2KMT2ANPC1
SCHEMBL14620099 0.78 KMT2A (0.51) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KMT2A
SCHEMBL1561845 0.78 HPSE (0.53) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KMT2A
SCHEMBL14620100 0.77 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KMT2A
SCHEMBL24437289 0.77 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KMT2A
SCHEMBL10284047 0.76 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 US disclosed
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof INSTITUT CURIE (FR) 2026-01-20 US disclosed
US-20220233673-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2022-07-28 US disclosed
EP-1644426-B1 POSITIVE PHOTORESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO LTD (JP) 2009-06-17 EP disclosed
US-7157205-B2 Intermediate layer composition for multilayer resist process, pattern-forming process using the same, and laminate FUJI PHOTO FILM CO., LTD. (JP) 2007-01-02 US disclosed
US-7132213-B2 Positive photoresist composition and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2006-11-07 US disclosed
US-20060166131-A1 Positive photoresist composition and method of forming resist pattern TOKYO OHKA KOGYO, CO., LTD. (JP) 2006-07-27 US disclosed
EP-1644426-A1 POSITIVE PHOTORESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2006-04-12 EP disclosed
WO-2005007718-A1 POSITIVE PHOTORESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN TOKYO OHKA KOGYO CO., LTD. (JP) 2005-01-27 WO disclosed
US-4242507-A Sulfonic acid esters FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527854-B2 Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof STXBP1, RNGTT, UPF1 ALDH1A1 4838/4885SMN1; SMN2 431/4885CYP1A2 4734/4885
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF STXBP1, HBB, UPF1 ALDH1A1 4710/4885SMN1; SMN2 526/4885CYP1A2 4748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.