Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | TCF4 | P15884 | 1/20 | 0.65 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560173 | 0.90 | CYP2C9 (0.80) | CYP2C9ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL1073233 | 0.90 | CYP2C9 (1.00) | CYP2C9ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL24102911 | 0.88 | CYP2C9 (0.76) | CYP2C9ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL29535237 | 0.88 | CYP2C9 (0.76) | CYP2C9ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL22391857 | 0.88 | CYP2C9 (0.76) | CYP2C9ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL16119560 | 0.88 | CYP2C9 (0.76) | CYP2C9ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL7569777 | 0.87 | CYP2C9 (0.64) | CYP2C9ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL15830615 | 0.87 | CYP2C9 (0.64) | CYP2C9ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL15830581 | 0.87 | ALDH1A1 (0.81) | CYP2C9ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL15830513 | 0.87 | CYP2C9 (0.64) | CYP2C9ALDH1A1LMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322035-A1 | Enzyme Inhibitors | UNIVERSITY OF SUNDERLAND (GB) | 2015-11-12 | — | — | US | disclosed |
| WO-2014096864-A9 | ENZYME INHIBITORS | UNIVERSITY OF SUNDERLAND (GB) | 2015-03-05 | — | — | WO | disclosed |
| WO-2014096864-A1 | ENZYME INHIBITORS | UNIVERSITY OF SUNDERLAND (GB) | 2014-06-26 | — | — | WO | disclosed |
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322035-A1 | Enzyme Inhibitors | TXNRD3, TXNRD2, TXNRD1 | CYP2C9 1962/4885ALDH1A1 687/4885LMNA 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.