Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8993559 | 0.84 | LMNA (0.43) | GABRA1GABRB2ALDH1A1CDK1CCNB1 | |
| SCHEMBL9015283 | 0.84 | LMNA (0.43) | GABRA1GABRB2ALDH1A1CDK1CCNB1 | |
| SCHEMBL7564062 | 0.71 | KDM4E (0.55) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL3363408 | 0.71 | KDM4E (0.55) | ALDH1A1CDK1CCNB1GSK3AGSK3B | |
| SCHEMBL4165394 | 0.67 | GABRA1 (0.50) | GABRA1GABRB2ALDH1A1MAP1LC3BMAP1LC3A | |
| SCHEMBL8539519 | 0.67 | GABRA1 (0.50) | GABRA1GABRB2 | |
| SCHEMBL12676476 | 0.67 | MAPT (0.50) | GABRA1GABRB2ALDH1A1LMNATDP1 | |
| SCHEMBL647401 | 0.66 | OPRM1 (0.54) | GABRA1GABRB2LMNAMAPTKDM4E | |
| SCHEMBL10160176 | 0.65 | GAA (0.44) | ALDH1A1LMNATDP1MAPT | |
| Phosphoric Acid SCHEMBL29099239 | 0.65 | GABRA1 (0.46) | GABRA1GABRB2LMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746551-B1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | UNIV OHIO STATE RES FOUND (US) | 2002-09-04 | — | — | EP | claimed |
| EP-0746551-B1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | UNIV OHIO STATE RES FOUND (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-0746551-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5504108-A | ANTIAGGLOMERANTS, ANTIARTHRITIC AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1995023139-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-08-31 | — | — | WO | disclosed |