Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | UQCRB | P14927 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CCR9 | P51686 | 2/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574025 | 0.85 | FFAR4 (0.56) | FFAR4UQCRBHSD17B2LMNAMAPT | |
| SCHEMBL7579848 | 0.81 | GAA (0.50) | UQCRBHSD17B2LMNAMAPTALDH1A1 | |
| SCHEMBL7572310 | 0.77 | ALDH1A1 (0.66) | FFAR4UQCRBHSD17B2LMNAMAPT | |
| SCHEMBL1348234 | 0.75 | LMNA (0.75) | UQCRBHSD17B2LMNAMAPTALDH1A1 | |
| SCHEMBL7589382 | 0.72 | FFAR4 (0.71) | FFAR4MAPTALDH1A1CYP2C9GAA | |
| SCHEMBL12407078 | 0.71 | FFAR4 (0.55) | FFAR4LMNAMAPTPOLBGAA | |
| SCHEMBL12096927 | 0.71 | FFAR4 (0.49) | FFAR4LMNAMAPTALDH1A1GAA | |
| SCHEMBL10143422 | 0.70 | FFAR4 (0.57) | FFAR4GAAKMT2ACCR9 | |
| SCHEMBL7570701 | 0.70 | PTGES2 (0.60) | FFAR4UQCRBHSD17B2LMNAMAPT | |
| SCHEMBL29087421 | 0.70 | KMT2A (0.64) | FFAR4GAAKMT2AMEN1CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |