Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.56 |
| ▸ | KRAS | P01116 | 8/20 | 0.54 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.52 |
| ▸ | HINT1 | P49773 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5061620 | 1.00 | NT5E (0.60) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL1697432 | 0.92 | NT5E (0.61) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL6027526 | 0.92 | NT5E (0.61) | NT5ETGM2IMPDH2KRASFUT5 | |
| Guanosine SCHEMBL8429254 | 0.90 | TGM2 (0.55) | NT5ETGM2IMPDH2KRASFUT5 | |
| Guanosine SCHEMBL3264840 | 0.90 | TGM2 (0.55) | NT5ETGM2IMPDH2KRASFUT5 | |
| Guanosine SCHEMBL4816737 | 0.90 | TGM2 (0.55) | NT5ETGM2IMPDH2KRASFUT5 | |
| SCHEMBL1269745 | 0.88 | NT5E (0.61) | NT5ETGM2IMPDH2KRASFUT5 | |
| Demannose SCHEMBL20746287 | 0.88 | TGM2 (0.66) | NT5ETGM2IMPDH2KRASFUT5 | |
| Demannose SCHEMBL2182862 | 0.88 | TGM2 (0.66) | NT5ETGM2IMPDH2KRASFUT5 | |
| Demannose SCHEMBL4290630 | 0.88 | TGM2 (0.66) | NT5ETGM2IMPDH2KRASFUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020068331-A1 | Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose | WONG CHI-HUEY (US) | 2002-06-06 | — | — | US | claimed |
| EP-0642526-B1 | PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE | SCRIPPS RESEARCH INST (US) | 1998-12-23 | — | — | EP | claimed |
| EP-0642526-A4 | PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE. | SCRIPPS RESEARCH INST (US) | 1996-04-10 | — | — | EP | claimed |
| EP-0642526-A1 | PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-03-15 | — | — | EP | claimed |
| WO-1993008205-A1 | PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-04-29 | — | — | WO | claimed |
| EP-0958352-A1 | METHOD FOR THE PRODUCTION OF NDP-SUGAR | FORSCHUNGSZENTRUM JÜLICH GMBH (DE) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998033894-A1 | METHOD FOR THE PRODUCTION OF NDP-SUGAR | Forschungszentrum Jülich GmbH (DE) | 1998-08-06 | — | — | WO | disclosed |