Guanosine

Guanosine

SCHEMBL4816737

Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=C[C@@H](OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.55
NT5E P21589 1/20 0.54
KRAS P01116 5/20 0.51
IMPDH2 P12268 6/20 0.50
FUT5 Q11128 1/20 0.50
HPGD P15428 1/20 0.50
P2RY2 P41231 1/20 0.49
P2RY4 P51582 1/20 0.49
P2RY6 Q15077 1/20 0.49
HINT1 P49773 1/20 0.49
GSK3A P49840 2/20 0.47
RPS6KA3 P51812 2/20 0.47
MAPK14 Q16539 2/20 0.47
IMPDH1 P20839 2/20 0.47
DCPS Q96C86 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanosine SCHEMBL8429254 1.00 TGM2 (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL3264840 1.00 TGM2 (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL1421810 0.93 TGM2 (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL28048641 0.92 TGM2 (0.57) TGM2NT5EKRASIMPDH2FUT5
SCHEMBL5061620 0.90 NT5E (0.60) TGM2NT5EKRASIMPDH2FUT5
SCHEMBL7571229 0.90 NT5E (0.60) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL7571212 0.89 NT5E (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL6027663 0.89 NT5E (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL6066347 0.87 NT5E (0.69) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL9827513 0.87 NT5E (0.69) TGM2NT5EKRASIMPDH2FUT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-120020261-A Method for total synthesis of N-glycan 中国科学院上海药物研究所 2025-05-20 CN claimed
WO-2025019764-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS MATTERWORKS INC (US) 2025-01-23 WO claimed
US-20240418701-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE NANJING UNIVERSITY (CN) 2024-12-19 US claimed
CN-119120439-A UDP/GDP-glucose epimerase for catalytic synthesis of UDP/GDP-mannose 江南大学 2024-12-13 CN claimed
EP-4437319-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION Matterworks Inc (US) 2024-10-02 EP claimed
EP-4413379-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE Nanjing University (CN) 2024-08-14 EP claimed
CN-118103711-A Single molecule identification with reactive heterogeneous nanopores 南京大学 2024-05-28 CN claimed
CN-117683833-A Method for preparing nucleotide sugar from nucleoside monophosphate 山东大学 2024-03-12 CN claimed
CN-117187344-A HPLC method for measuring activity of polyterpene alcohol phosphomannosyltransferase 济宁医学院 2023-12-08 CN claimed
US-20230137741-A1 METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION MATTERWORKS INC 2023-05-04 US claimed
WO-2023056960-A1 SINGLE MOLECULE IDENTIFICATION WITH A REACTIVE HETERO-NANOPORE NANJING UNIVERSITY (CN) 2023-04-13 WO claimed
US-20230060588-A1 METHODS OF AMELIORATING AND/OR PREVENTING CORONAVIRUS-RELATED INFECTIONS Glycure LLC (US) 2023-03-02 US claimed
CN-111793664-A Method for biologically preparing mannose glyceric acid 中国科学院天津工业生物技术研究所 2020-10-20 CN claimed
US-7335500-B2 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose THE SCRIPPS RESEARCH INSTITUTE (US) 2008-02-26 US claimed
US-20020068331-A1 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose WONG CHI-HUEY (US) 2002-06-06 US claimed
EP-0642526-B1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE SCRIPPS RESEARCH INST (US) 1998-12-23 EP claimed
EP-0642526-A4 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE. SCRIPPS RESEARCH INST (US) 1996-04-10 EP claimed
EP-0642526-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1995-03-15 EP claimed
WO-1993008205-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1993-04-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230060588-A1 METHODS OF AMELIORATING AND/OR PREVENTING CORONAVIRUS-RELATED INFECTIONS FUT5, FUT6, SIGLEC7 TGM2 908/4885NT5E 378/4885KRAS 4170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.