Guanosine

Guanosine

SCHEMBL3264840

Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1.O=CC(OP(=O)(O)OP(=O)(O)O)C(O)C(O)C(O)CO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.55
NT5E P21589 1/20 0.54
KRAS P01116 5/20 0.51
IMPDH2 P12268 6/20 0.50
FUT5 Q11128 1/20 0.50
HPGD P15428 1/20 0.50
P2RY2 P41231 1/20 0.49
P2RY4 P51582 1/20 0.49
P2RY6 Q15077 1/20 0.49
HINT1 P49773 1/20 0.49
GSK3A P49840 2/20 0.47
RPS6KA3 P51812 2/20 0.47
MAPK14 Q16539 2/20 0.47
IMPDH1 P20839 2/20 0.47
DCPS Q96C86 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanosine SCHEMBL8429254 1.00 TGM2 (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL4816737 1.00 TGM2 (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL1421810 0.93 TGM2 (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL28048641 0.92 TGM2 (0.57) TGM2NT5EKRASIMPDH2FUT5
SCHEMBL5061620 0.90 NT5E (0.60) TGM2NT5EKRASIMPDH2FUT5
SCHEMBL7571229 0.90 NT5E (0.60) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL7571212 0.89 NT5E (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL6027663 0.89 NT5E (0.55) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL6066347 0.87 NT5E (0.69) TGM2NT5EKRASIMPDH2FUT5
Guanosine SCHEMBL9827513 0.87 NT5E (0.69) TGM2NT5EKRASIMPDH2FUT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2508610-A1 Plants having enhanced yield-related traits and a method for making the same BASF Plant Science GmbH (DE) 2012-10-10 EP disclosed
US-20100199380-A1 PLANTS HAVING ENHANCED YIELD-RELATED TRAITS AND A METHOD FOR MAKING THE SAME BASF PLANT SCIENCE GMBH (DE) 2010-08-05 US disclosed
WO-2009003977-A9 PLANTS HAVING ENHANCED YIELD-RELATED TRAITS AND A METHOD FOR MAKING THE SAME BASF PLANT SCIENCE GMBH (DE) 2010-03-04 WO disclosed
EP-2078090-A2 PLANTS HAVING ENHANCED YIELD-RELATED TRAITS AND A METHOD FOR MAKING THE SAME BASF Plant Science GmbH (DE) 2009-07-15 EP disclosed
WO-2009003977-A2 PLANTS HAVING ENHANCED YIELD-RELATED TRAITS AND A METHOD FOR MAKING THE SAME BASF PLANT SCIENCE GMBH (DE) 2009-01-08 WO disclosed