Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572957 | 0.90 | RAB9A (0.48) | ALDH1A1MEN1KMT2AP2RX7KDM4E | |
| SCHEMBL7570515 | 0.87 | P2RX7 (0.47) | ALDH1A1MEN1KMT2AP2RX7KDM4E | |
| Hydrochloric Acid SCHEMBL7572364 | 0.86 | MAPT (0.47) | ALDH1A1MEN1KMT2AP2RX7KDM4E | |
| SCHEMBL7571682 | 0.85 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AP2RX7EPHX2 | |
| SCHEMBL7578023 | 0.85 | P2RX7 (0.49) | ALDH1A1MEN1KMT2AP2RX7KDM4E | |
| SCHEMBL7572642 | 0.79 | P2RX7 (0.43) | ALDH1A1MEN1KMT2AP2RX7KDM4E | |
| Hydrochloric Acid SCHEMBL7570206 | 0.76 | P2RX7 (0.48) | ALDH1A1MEN1KMT2AP2RX7KDM4E | |
| SCHEMBL7569262 | 0.74 | P2RX7 (0.57) | ALDH1A1MEN1KMT2AP2RX7HPGD | |
| Trifluoroacetic Acid SCHEMBL7577511 | 0.74 | P2RX7 (0.41) | ALDH1A1MEN1KMT2AP2RX7KDM4E | |
| SCHEMBL7571707 | 0.74 | P2RX7 (0.57) | ALDH1A1MEN1KMT2AP2RX7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | claimed |