Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571514 | 0.90 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2P2RX7LMNAMEN1 | |
| SCHEMBL7578023 | 0.86 | P2RX7 (0.49) | P2RX7MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7572364 | 0.84 | MAPT (0.47) | RAB9ASMN1; SMN2P2RX7LMNAMAPT | |
| SCHEMBL7571707 | 0.84 | P2RX7 (0.57) | RAB9ASMN1; SMN2P2RX7MEN1KMT2A | |
| SCHEMBL7572642 | 0.80 | P2RX7 (0.43) | SMN1; SMN2P2RX7MEN1KMT2AALDH1A1 | |
| SCHEMBL7570515 | 0.79 | P2RX7 (0.47) | P2RX7LMNAHTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7570206 | 0.77 | P2RX7 (0.48) | P2RX7MAPTMEN1KMT2ACYP1A2 | |
| Trifluoroacetic Acid SCHEMBL7577511 | 0.76 | P2RX7 (0.41) | SMN1; SMN2P2RX7MEN1KMT2AALDH1A1 | |
| SCHEMBL7571682 | 0.75 | ALDH1A1 (0.60) | SMN1; SMN2P2RX7LMNAMEN1KMT2A | |
| SCHEMBL7576813 | 0.75 | MEN1 (0.48) | P2RX7MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | claimed |