Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | IDH1 | O75874 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95317 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1IDH1MEN1LMNA | |
| SCHEMBL7580547 | 0.86 | IDH1 (0.71) | SMN1; SMN2L3MBTL1IDH1 | |
| SCHEMBL7571585 | 0.86 | ALDH1A1 (0.66) | SMN1; SMN2L3MBTL1IDH1MEN1LMNA | |
| SCHEMBL23832727 | 0.86 | CA2 (0.48) | IDH1MEN1LMNAMAPTKMT2A | |
| SCHEMBL30218187 | 0.86 | CA2 (0.48) | IDH1MEN1LMNAMAPTKMT2A | |
| SCHEMBL7572373 | 0.86 | L3MBTL1 (0.67) | SMN1; SMN2L3MBTL1IDH1MEN1LMNA | |
| SCHEMBL7571531 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2L3MBTL1IDH1MEN1LMNA | |
| SCHEMBL25754729 | 0.83 | LMNA (0.67) | SMN1; SMN2L3MBTL1MEN1LMNAMAPT | |
| SCHEMBL15658306 | 0.82 | GUSB (0.56) | SMN1; SMN2MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL25754750 | 0.81 | MEN1 (0.51) | SMN1; SMN2L3MBTL1IDH1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |