Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ITGA1 | P56199 | 3/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588364 | 0.86 | SLC40A1 (0.63) | SLC40A1KMT2AMEN1ITGA1MCL1 | |
| SCHEMBL7577319 | 0.85 | SLC40A1 (0.63) | SLC40A1KMT2AMEN1ITGA1MCL1 | |
| SCHEMBL4799558 | 0.79 | SLC40A1 (0.56) | SLC40A1KMT2AMEN1ITGA1MCL1 | |
| SCHEMBL4799566 | 0.79 | ALDH1A1 (0.63) | SLC40A1KMT2AMEN1ITGA1MCL1 | |
| SCHEMBL11973322 | 0.79 | SLC40A1 (1.00) | SLC40A1KMT2AMEN1 | |
| SCHEMBL30925515 | 0.79 | SLC40A1 (1.00) | SLC40A1KMT2AMEN1 | |
| SCHEMBL1319104 | 0.78 | RECQL (0.69) | SLC40A1KMT2AMEN1RECQLMCL1 | |
| SCHEMBL7572387 | 0.77 | SLC40A1 (0.64) | SLC40A1KMT2AMEN1RECQLMCL1 | |
| SCHEMBL23141245 | 0.76 | ACLY (0.60) | SLC40A1KMT2AMEN1ITGA1HPGD | |
| SCHEMBL31261221 | 0.76 | ACLY (0.60) | SLC40A1KMT2AMEN1ITGA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |