Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.64 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | EDNRB | P24530 | 3/20 | 0.54 |
| ▸ | EDNRA | P25101 | 3/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.49 |
| ▸ | CCR4 | P51679 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594250 | 0.88 | SLC40A1 (0.66) | SLC40A1HSD11B1EDNRBEDNRAALDH1A1 | |
| SCHEMBL7578810 | 0.85 | SLC40A1 (0.64) | SLC40A1HSD11B1EDNRBEDNRAPTGES2 | |
| SCHEMBL7588152 | 0.79 | SLC40A1 (0.59) | SLC40A1HSD11B1EDNRBEDNRAALDH1A1 | |
| SCHEMBL11973501 | 0.79 | SLC40A1 (1.00) | SLC40A1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13510463 | 0.79 | HSD11B1 (0.68) | SLC40A1HSD11B1MEN1KMT2AEDNRB | |
| SCHEMBL12407075 | 0.78 | PKM (0.60) | SLC40A1HSD11B1EDNRBEDNRAALDH1A1 | |
| SCHEMBL3768958 | 0.77 | HSD11B1 (0.60) | SLC40A1HSD11B1EDNRBEDNRAKEAP1 | |
| SCHEMBL7571597 | 0.77 | SLC40A1 (0.64) | SLC40A1MEN1KMT2ARECQLKEAP1 | |
| SCHEMBL7591248 | 0.77 | HSD11B1 (0.63) | SLC40A1HSD11B1EDNRBEDNRAPTGES2 | |
| SCHEMBL7591197 | 0.77 | PTGES2 (0.59) | SLC40A1HSD11B1EDNRBEDNRAPTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |