⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573935 | 0.83 | ABCB11 (0.31) | — | |
| SCHEMBL7572988 | 0.74 | PTGES (0.35) | — | |
| SCHEMBL8013770 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL7570704 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL7578532 | 0.69 | LMNA (0.32) | — | |
| SCHEMBL8016482 | 0.68 | SLC1A3 (0.37) | — | |
| SCHEMBL8017823 | 0.68 | ABCB11 (0.32) | — | |
| SCHEMBL8021086 | 0.67 | L3MBTL1 (0.30) | — | |
| SCHEMBL7577303 | 0.67 | HDAC4 (0.30) | — | |
| SCHEMBL7571141 | 0.67 | ABCB11 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020198382-A1 | Oxiran carboxylic acids for the treatment of diabetes | HORST P.O. WOLF (DE) | 2002-12-26 | — | — | US | disclosed |
| US-6013666-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION | Jew, Sang Sup (KR) | 2000-01-11 | — | — | US | disclosed |
| WO-1998000422-A1 | OXIRANE CARBOXYLIC ACID DERIVATIVE AND ITS MANUFACTURING METHOD | JEW SANG SUP (KR) | 1998-01-08 | — | — | WO | disclosed |