Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.50 |
| ▸ | ITGAV | P06756 | 4/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520753 | 0.84 | KMT2A (0.48) | ITGB3ITGAVITGA2BNPC1ITGB1 | |
| SCHEMBL7498232 | 0.84 | NR1H4 (0.41) | ITGB3ITGA2BALDH1A1MAPTNPC1 | |
| SCHEMBL7373335 | 0.77 | ITGB3 (0.71) | ITGB3ITGAVITGA2BALDH1A1MAPT | |
| SCHEMBL7458369 | 0.76 | ITGB3 (0.72) | ITGB3ITGAVITGA2BALDH1A1MAPT | |
| Bicarbonate SCHEMBL7767424 | 0.75 | ALDH1A1 (0.52) | ITGB3ITGAVITGA2BALDH1A1MAPT | |
| SCHEMBL7765701 | 0.74 | ALDH1A1 (0.46) | ITGB3ITGAVITGA2BALDH1A1MAPT | |
| SCHEMBL7498241 | 0.73 | KMT2A (0.39) | ITGB3ITGA2BALDH1A1MAPTNPC1 | |
| SCHEMBL7353478 | 0.73 | ALDH1A1 (0.49) | ITGB3ITGAVITGA2BALDH1A1MAPT | |
| SCHEMBL8520757 | 0.72 | KMT2A (0.51) | ITGB3ITGA2BALDH1A1MAPTNPC1 | |
| SCHEMBL7497389 | 0.72 | PARP1 (0.51) | ITGB3ITGAVITGA2BALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894084-B1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-06-26 | — | — | EP | claimed |