Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590525 | 0.87 | NPC1 (0.63) | TP53HPGDALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL7592227 | 0.81 | CCR2 (0.67) | TP53HPGDCCR2 | |
| SCHEMBL7595873 | 0.80 | TP53 (0.60) | TP53HPGDALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL1654078 | 0.77 | ALDH1A1 (0.47) | TP53HPGDALDH1A1NPC1CCR2 | |
| SCHEMBL7594332 | 0.77 | ALDH1A1 (0.71) | TP53ALDH1A1NPC1KDM4EKMT2A | |
| SCHEMBL12352072 | 0.76 | BRAF (0.73) | ALDH1A1NPC1KMT2A | |
| SCHEMBL15888942 | 0.75 | CNKSR1 (0.65) | TP53HPGDALDH1A1KMT2ATSHR | |
| SCHEMBL26035691 | 0.75 | BRAF (0.70) | TP53HPGDALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL7590993 | 0.74 | CCR2 (0.66) | TP53ALDH1A1NPC1SMN1; SMN2CCR2 | |
| SCHEMBL7573015 | 0.74 | CCR2 (0.64) | TP53ALDH1A1NPC1SMN1; SMN2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |