Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565801 | 0.81 | SOAT2 (0.51) | SOAT2ACAT1SOAT1SLC6A4SLC6A3 | |
| SCHEMBL6209359 | 0.79 | LMNA (0.51) | SLC6A4SLC6A3SLC6A2ALDH1A1LMNA | |
| SCHEMBL28093470 | 0.78 | SOAT2 (0.60) | SOAT2ACAT1SOAT1MEN1ALDH1A1 | |
| SCHEMBL6208320 | 0.78 | LMNA (0.50) | SLC6A4SLC6A3SLC6A2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28177156 | 0.77 | SOAT2 (0.59) | SOAT2ACAT1SOAT1MEN1ALDH1A1 | |
| SCHEMBL6208716 | 0.76 | SLC6A4 (0.65) | SLC6A4SLC6A3SLC6A2KDM4EMEN1 | |
| SCHEMBL6492041 | 0.75 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2KDM4EMEN1 | |
| SCHEMBL6209826 | 0.75 | SLC6A3 (0.58) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7508542 | 0.75 | DPP4 (0.58) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6240339 | 0.74 | SLC6A3 (0.60) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020183384-A1 | Methods of treating nuclear factor-kappa B mediated diseases and disorders | CORNICELLI JOSEPH ANTHONY (US) | 2002-12-05 | — | — | US | claimed |
| EP-1236468-A1 | Sulfonylaminocarbonyl derivatives for the treatment of nuclear factor-kappa B mediated diseases and disorders | WARNER-LAMBERT COMPANY (US) | 2002-09-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183384-A1 | Methods of treating nuclear factor-kappa B mediated diseases and disorders | NFKBIA, IKBKB, RELA | SOAT2 324/4885ACAT1 231/4885SOAT1 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.