SCHEMBL6208320

SCHEMBL6208320

O=CNCC1(c2ccc(Br)cc2)CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.50
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
SLC6A4 P31645 10/20 0.45
SLC6A3 Q01959 10/20 0.45
SLC6A2 P23975 6/20 0.45
NPSR1 Q6W5P4 2/20 0.41
GAA P10253 1/20 0.41
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6209359 0.98 LMNA (0.51) LMNAALDH1A1SMN1; SMN2L3MBTL1POLB
SCHEMBL6492041 0.81 SLC6A4 (0.68) LMNASMN1; SMN2L3MBTL1SLC6A4SLC6A3
SCHEMBL6240339 0.80 SLC6A3 (0.60) SLC6A4SLC6A3SLC6A2
SCHEMBL6208716 0.79 SLC6A4 (0.65) LMNAALDH1A1SMN1; SMN2L3MBTL1POLB
SCHEMBL7573036 0.78 SOAT2 (0.51) LMNAALDH1A1SLC6A4SLC6A3SLC6A2
SCHEMBL6209826 0.78 SLC6A3 (0.58) SLC6A4SLC6A3SLC6A2
SCHEMBL6494934 0.76 SLC6A4 (0.63) LMNASLC6A4SLC6A3SLC6A2
SCHEMBL6231738 0.74 SLC6A3 (0.61) LMNASLC6A4SLC6A3SLC6A2
SCHEMBL16823453 0.74 SLC6A4 (0.62) LMNAALDH1A1SMN1; SMN2L3MBTL1POLB
SCHEMBL6209698 0.73 RORC (0.47) LMNASLC6A4SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11229590-B2 Sunscreen formulation SUN YIMIN (CN) 2022-01-25 US disclosed
US-20210361548-A1 A SUNSCREEN FORMULATION SUN YIMIN (CN) 2021-11-25 US disclosed
US-20050234096-A1 Tetrahydroisoquinoline derivatives BAYER HEALTHCARE AG (DE) 2005-10-20 US disclosed
US-20050154042-A1 N-alkyl pyrroles as HMG-CoA reductase inhibitors WARNER-LAMBERT COMPANY 2005-07-14 US disclosed
EP-1507763-A1 TETRAHYDROISOQUINOLINE DERIVATIVES Bayer HealthCare AG (DE) 2005-02-23 EP disclosed
WO-2003097607-A1 TETRAHYDROISOQUINOLINE DERIVATIVES BAYER HEALTHCARE AG (DE) 2003-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210361548-A1 A SUNSCREEN FORMULATION CUTA, BCAS2, SUN2 LMNA 1634/4885ALDH1A1 598/4885SMN1; SMN2 2909/4885
US-11229590-B2 Sunscreen formulation BCAS2, CUTA, SUN2 LMNA 1586/4885ALDH1A1 685/4885SMN1; SMN2 2747/4885
US-20050154042-A1 N-alkyl pyrroles as HMG-CoA reductase inhibitors HMGCR, DHCR7, CYP11A1 LMNA 657/4885ALDH1A1 1452/4885SMN1; SMN2 4781/4885
US-20050234096-A1 Tetrahydroisoquinoline derivatives PPARD, PPARG, PPARA LMNA 2034/4885ALDH1A1 2218/4885SMN1; SMN2 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.