SCHEMBL7573347

SCHEMBL7573347

O=c1oc2ccccc2cc1[C]1NCc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
RAB9A P51151 5/20 0.53
MAOB P27338 4/20 0.53
KDM4E B2RXH2 3/20 0.53
LMNA P02545 2/20 0.50
HPGD P15428 5/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
NPC1 O15118 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
GAA P10253 2/20 0.48
GAPDH P04406 2/20 0.48
NCOA1 Q15788 1/20 0.48
NCOA3 Q9Y6Q9 1/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
GPR35 Q9HC97 1/20 0.47
MAPT P10636 3/20 0.47
TP53 P04637 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517170 0.76 RAB9A (0.78) ALDH1A1RAB9AMAOBKDM4ELMNA
SCHEMBL177366 0.70 RAB9A (1.00) ALDH1A1RAB9AMAOBKDM4ELMNA
SCHEMBL30356319 0.70 RAB9A (1.00) ALDH1A1RAB9AMAOBKDM4ELMNA
SCHEMBL30417366 0.70 RAB9A (0.68) ALDH1A1RAB9AMAOBKDM4ELMNA
SCHEMBL4970506 0.69 MAOB (0.62) ALDH1A1RAB9AMAOBKDM4ELMNA
SCHEMBL7124845 0.69 MIF (0.70) ALDH1A1RAB9AMAOBKDM4ELMNA
SCHEMBL28590374 0.69 MAOB (0.70) ALDH1A1RAB9AMAOBKDM4ELMNA
SCHEMBL31156822 0.69 MAOB (0.73) ALDH1A1RAB9AMAOBKDM4ELMNA
SCHEMBL31156818 0.69 MAOB (0.73) ALDH1A1RAB9AMAOBKDM4ELMNA
SCHEMBL30108485 0.69 LMNA (0.77) ALDH1A1RAB9AMAOBKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020124330-A1 Coloration composition, process for obtaining the same and its use for the coloration of keratin fibres L'OREAL (FR) 2002-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020124330-A1 Coloration composition, process for obtaining the same and its use for the coloration of keratin fibres KRT18, TYR, OAT ALDH1A1 2980/4885RAB9A 3343/4885MAOB 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.