Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP13 | P45452 | 3/20 | 0.47 |
| ▸ | MMP14 | P50281 | 3/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595618 | 0.87 | ALDH1A1 (0.55) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL7571617 | 0.86 | TAAR1 (0.56) | MEN1KMT2AHTTALDH1A1AR | |
| SCHEMBL7572313 | 0.83 | CA12 (0.59) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL7570427 | 0.82 | AR (0.57) | MEN1KMT2AHTTALDH1A1ADAMTS4 | |
| SCHEMBL7570456 | 0.79 | MEN1 (0.51) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL7580123 | 0.76 | PGR (0.57) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL1714596 | 0.73 | — | — | |
| SCHEMBL16451223 | 0.71 | MEN1 (0.55) | MEN1KMT2AHTTALDH1A1POLB | |
| SCHEMBL7574913 | 0.71 | ALOX15 (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4519542 | 0.71 | HTT (0.71) | MEN1KMT2AHTTALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |