Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.50 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595618 | 0.81 | ALDH1A1 (0.55) | PGRLMNAKMT2AMEN1HTT | |
| SCHEMBL7572313 | 0.77 | CA12 (0.59) | KMT2AMEN1HTTALDH1A1MAPT | |
| SCHEMBL7571617 | 0.77 | TAAR1 (0.56) | KMT2ABCL2L1MCL1MEN1HTT | |
| SCHEMBL7570456 | 0.77 | MEN1 (0.51) | LMNANPSR1KMT2AMEN1HTT | |
| SCHEMBL7573869 | 0.76 | MEN1 (0.54) | NPSR1KMT2AMEN1HTTALDH1A1 | |
| SCHEMBL7570427 | 0.73 | AR (0.57) | LMNAPTGES2KMT2ABCL2L1MCL1 | |
| SCHEMBL15787094 | 0.72 | APEX1 (0.62) | KMT2ATDP1ALDH1A1GAA | |
| SCHEMBL14414978 | 0.72 | DRD2 (0.45) | LMNAKMT2ATDP1MEN1HTT | |
| SCHEMBL7579053 | 0.71 | PGR (0.75) | PGRLMNAPTGES2KMT2AMEN1 | |
| SCHEMBL10772979 | 0.71 | TBXA2R (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |