Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949348 | 0.78 | GSK3B (0.67) | GSK3BMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7574156 | 0.75 | MEN1 (0.57) | GSK3BMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL27728396 | 0.75 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL30949339 | 0.75 | GSK3B (0.73) | GSK3BMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11515229 | 0.74 | MAOA (1.00) | GSK3BMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL30949349 | 0.72 | GSK3B (0.69) | GSK3BMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL30949350 | 0.72 | GSK3B (0.69) | GSK3BMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL24193545 | 0.71 | LMNA (0.55) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL30949324 | 0.71 | KMT2A (0.58) | GSK3BMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL25726431 | 0.71 | GSK3B (0.58) | GSK3BMEN1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062763-A2 | INHIBITION OF RAF KINASE USING QUINOLYL ISOQUINOLYL OR PYRIDYL UREAS | BAYER CORPORATION (US) | 2002-08-15 | — | — | WO | disclosed |