Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGAV | P06756 | 2/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950440 | 0.87 | FOLH1 (0.64) | FOLH1SIRT2SIRT1CAPN1CAPN2 | |
| SCHEMBL13324010 | 0.86 | SIRT2 (0.61) | FOLH1SIRT2SIRT1CAPN1CAPN2 | |
| SCHEMBL6363995 | 0.84 | CTSK (0.54) | FOLH1CAPN1CAPN2 | |
| SCHEMBL30869144 | 0.82 | HTT (0.58) | FOLH1TGM2 | |
| SCHEMBL19925534 | 0.81 | FOLH1 (0.64) | FOLH1SIRT2SIRT1PPARGPPARA | |
| SCHEMBL19307785 | 0.81 | FOLH1 (0.64) | FOLH1SIRT2SIRT1PPARGPPARA | |
| SCHEMBL9698236 | 0.81 | FOLH1 (0.64) | FOLH1SIRT2SIRT1PPARGPPARA | |
| SCHEMBL24238520 | 0.81 | FOLH1 (0.64) | FOLH1SIRT2SIRT1PPARGPPARA | |
| SCHEMBL9697060 | 0.81 | FOLH1 (0.64) | FOLH1SIRT2SIRT1PPARGPPARA | |
| SCHEMBL29467642 | 0.81 | LMNA (0.54) | FOLH1SIRT2SIRT1CAPN1CAPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002086139-A1 | ANTIBIOTIC AA 896 ANALOGS | WYETH HOLDINGS CORPORATION (US) | 2002-10-31 | — | — | WO | disclosed |