Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574531 | 0.78 | TSHR (0.42) | HSP90AA1HSP90AB1ALDH1A1TSHRMEN1 | |
| SCHEMBL18463980 | 0.78 | LMNA (0.46) | GAA | |
| SCHEMBL7102004 | 0.76 | MAOA (0.41) | ALDH1A1TSHRTDP1MAOAMAOB | |
| SCHEMBL10599295 | 0.72 | ALDH1A1 (0.38) | HSP90AA1HSP90AB1ALDH1A1TSHRMEN1 | |
| SCHEMBL7127844 | 0.71 | GABRA1 (0.42) | HSP90AA1HSP90AB1ALDH1A1TSHRMEN1 | |
| SCHEMBL7550163 | 0.71 | ALDH1A1 (0.58) | HSP90AA1HSP90AB1ALDH1A1TSHRMEN1 | |
| SCHEMBL19130505 | 0.71 | GABRA1 (0.42) | HSP90AA1HSP90AB1ALDH1A1TSHRMEN1 | |
| SCHEMBL24538831 | 0.69 | RIPK1 (0.40) | HSP90AA1HSP90AB1ALDH1A1TSHRMEN1 | |
| SCHEMBL18759138 | 0.69 | ALDH1A1 (0.36) | HSP90AA1HSP90AB1ALDH1A1TSHRMEN1 | |
| SCHEMBL498531 | 0.69 | NPC1 (0.45) | ALDH1A1TSHRMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945420-B1 | Process for the preparation of bisphenols | MITSUI CHEMICALS INC (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6316677-B1 | REACTING PHENOLIC COMPOUND WITH DIALKYLBENZENE, BIS(HYDROXYALKYL)BENZENE, OR (HYDROXYALKYL)-ALKENYLBENZENE; NEUTRALIZATION USING ANION EXCHANGE RESIN; CONCENTRATION, ISOLATION | MITSUI CHEMICALS, INC. (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-0945420-A1 | Process for the preparation of bisphenols | Mitsui Chemicals, Inc. (JP) | 1999-09-29 | — | — | EP | disclosed |