Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 7/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572602 | 0.86 | SIRT2 (0.49) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL6360549 | 0.82 | SIRT2 (0.48) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL6360553 | 0.82 | SIRT2 (0.48) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL6358666 | 0.80 | CTSS (0.69) | CTSLCTSSCTSB | |
| SCHEMBL6361534 | 0.78 | CTSS (0.57) | CTSLCTSSCTSB | |
| SCHEMBL6427219 | 0.78 | CA2 (0.61) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL7348318 | 0.78 | CA2 (0.61) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL13610345 | 0.78 | CA2 (0.61) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL7715048 | 0.76 | CTSL (0.71) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL13870510 | 0.76 | CA2 (0.59) | SIRT2SIRT1SIRT3CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002086139-A1 | ANTIBIOTIC AA 896 ANALOGS | WYETH HOLDINGS CORPORATION (US) | 2002-10-31 | — | — | WO | disclosed |