Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050042 | 1.00 | PTPN1 (0.41) | PTPN1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL5837579 | 0.84 | PTPN1 (0.53) | PTPN1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL5837572 | 0.84 | PTPN1 (0.53) | PTPN1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL7701502 | 0.79 | HPGD (0.43) | HPGDKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7564276 | 0.78 | CYP1A2 (0.39) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL7582515 | 0.75 | HPGD (0.37) | HPGDKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7699460 | 0.74 | NPC1 (0.48) | HPGDKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7698367 | 0.74 | KDM4E (0.50) | PTPN1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL7700382 | 0.74 | ALDH1A1 (0.37) | HPGDKDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL7699527 | 0.74 | KDM4E (0.50) | PTPN1HPGDKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214324-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019830-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | disclosed |