Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884772 | 0.81 | TSHR (0.39) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL14311953 | 0.76 | LMNA (0.40) | ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL786633 | 0.73 | ALDH1A1 (0.46) | ALDH1A1RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL2023930 | 0.73 | PKN1 (0.35) | ALDH1A1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL6665883 | 0.71 | RAB9A (0.57) | ALDH1A1FNTAFNTBRAB9ASMN1; SMN2 | |
| SCHEMBL786641 | 0.69 | KMT2A (0.53) | ALDH1A1RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL17065209 | 0.68 | ADORA3 (0.36) | ALDH1A1RAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL722287 | 0.66 | IGFBP3 (0.44) | ALDH1A1RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL724208 | 0.65 | ALDH1A1 (0.48) | ALDH1A1RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL724793 | 0.65 | HTT (0.41) | ALDH1A1RAB9ASMN1; SMN2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061896-A1 | Imidazopyrimidine nucleoside analogues with anti-HIV activity | BIOCHEM PHARMA, INC. (CA) | 2002-05-23 | — | — | US | disclosed |
| WO-2001049700-A1 | IMIDAZOPYRIMIDINE NUCLEOSIDE ANALOGUES WITH ANTI-HIV ACTIVITY | BIOCHEM PHARMA INC. (CA) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061896-A1 | Imidazopyrimidine nucleoside analogues with anti-HIV activity | TYMP, PNP, SLC29A1 | ALDH1A1 176/4885FNTA 1316/4885FNTB 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.