Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589226 | 0.85 | SLC6A2 (0.37) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7575967 | 0.73 | SLC6A2 (0.33) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8479508 | 0.69 | ITGAV (0.49) | — | |
| SCHEMBL8479505 | 0.64 | ITGAV (0.49) | — | |
| SCHEMBL20589146 | 0.63 | DPP7 (0.41) | SLC6A2SLC6A3L3MBTL1 | |
| SCHEMBL8483640 | 0.60 | ITGAV (0.47) | — | |
| SCHEMBL10505583 | 0.59 | ALDH1A1 (0.61) | L3MBTL1 | |
| SCHEMBL9023631 | 0.58 | ITGB3 (0.47) | — | |
| SCHEMBL4577442 | 0.58 | L3MBTL1 (0.63) | L3MBTL1 | |
| SCHEMBL10649966 | 0.57 | PKM (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946165-A4 | INTEGRIN ANTAGONISTS | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0946165-A1 | INTEGRIN ANTAGONISTS | Merck & Co., Inc. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998018460-A1 | INTEGRIN ANTAGONISTS | MERCK & CO., INC. (US) | 1998-05-07 | — | — | WO | disclosed |