SCHEMBL757610

SCHEMBL757610

CCN(CC)CCCCN(CCCCN(CC)CC)CCCCN(CC)CC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.46
HRH4 Q9H3N8 2/20 0.40
HRH3 Q9Y5N1 2/20 0.40
SLC2A1 P11166 1/20 0.39
ALDH1A1 P00352 2/20 0.39
KCNH2 Q12809 2/20 0.39
CHRM2 P08172 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39
CHRM1 P11229 1/20 0.39
DRD1 P21728 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
OPRM1 P35372 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
PAOX Q6QHF9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5990364 0.96 SIGMAR1 (0.44) SIGMAR1HRH4HRH3ALDH1A1KCNH2
SCHEMBL757439 0.96 SIGMAR1 (0.44) SIGMAR1HRH4HRH3ALDH1A1KCNH2
SCHEMBL234338 0.96 SIGMAR1 (0.48) SIGMAR1HRH4HRH3SLC2A1ALDH1A1
SCHEMBL15052279 0.96 SIGMAR1 (0.48) SIGMAR1HRH4HRH3SLC2A1ALDH1A1
SCHEMBL1313942 0.92 SIGMAR1 (0.46) SIGMAR1HRH4HRH3SLC2A1ALDH1A1
SCHEMBL2142541 0.92 SIGMAR1 (0.46) SIGMAR1HRH4HRH3SLC2A1ALDH1A1
SCHEMBL28723073 0.92 SIGMAR1 (0.46) SIGMAR1HRH4HRH3SLC2A1ALDH1A1
SCHEMBL2141035 0.92 SIGMAR1 (0.46) SIGMAR1HRH4HRH3SLC2A1ALDH1A1
SCHEMBL2137948 0.92 SIGMAR1 (0.46) SIGMAR1HRH4HRH3SLC2A1ALDH1A1
SCHEMBL2564528 0.92 SIGMAR1 (0.46) SIGMAR1HRH4HRH3SLC2A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240351866-A1 PROCESS FOR THE PRODUCTION OF HYDROGEN THROUGH ELECTRIFICATION OF WATER GAS SHIFT REACTION TOTALENERGIES ONETECH (FR) 2024-10-24 US disclosed
US-20240287400-A1 NEW GASOLINE ADDITIVE PACKAGES BASF SE (DE) 2024-08-29 US disclosed
WO-2024149635-A1 BRANCHED AMINES AS ADDITIVES FOR GASOLINE FUELS BASF SE (DE) 2024-07-18 WO disclosed
US-20240240000-A1 POLYISOBUTENE DERIVATIVES AS AN ADDITIVE IN RUBBERS BASF SE (DE) 2024-07-18 US disclosed
EP-4399178-A1 PROCESS FOR THE PRODUCTION OF HYDROGEN THROUGH ELECTRIFICATION OF WATER GAS SHIFT REACTION TotalEnergies OneTech (FR) 2024-07-17 EP disclosed
EP-4355845-A1 NEW GASOLINE ADDITIVE PACKAGES BASF SE (DE) 2024-04-24 EP disclosed
US-20240101919-A1 BRANCHED PRIMARY ALKYL AMINES AS ADDITIVES FOR GASOLINE FUELS BASF SE (DE) 2024-03-28 US disclosed
EP-4326813-A1 POLYISOBUTENE DERIVATIVES AS AN ADDITIVE IN RUBBERS BASF SE (DE) 2024-02-28 EP disclosed
CN-117500900-A Novel gasoline additive package 巴斯夫欧洲公司 2024-02-02 CN disclosed
EP-4284902-A1 BRANCHED PRIMARY ALKYL AMINES AS ADDITIVES FOR GASOLINE FUELS BASF SE (DE) 2023-12-06 EP disclosed
WO-2022263254-A1 NEW GASOLINE ADDITIVE PACKAGES BASF SE (DE) 2022-12-22 WO disclosed
WO-2022223345-A1 POLYISOBUTENE DERIVATIVES AS AN ADDITIVE IN RUBBERS BASF SE (DE) 2022-10-27 WO disclosed
WO-2022161803-A1 BRANCHED PRIMARY ALKYL AMINES AS ADDITIVES FOR GASOLINE FUELS BASF SE (DE) 2022-08-04 WO disclosed
US-9938479-B2 Use of amines and/or Mannich adducts in fuel and lubricant compositions for direct-injection spark ignition engines BASF SE (DE) 2018-04-10 US disclosed
US-20160222309-A1 USE OF AMINES AND/OR MANNICH ADDUCTS IN FUEL AND LUBRICANT COMPOSITIONS FOR DIRECT-INJECTION SPARK IGNITION ENGINES BASF SE (DE) 2016-08-04 US disclosed
US-9309475-B2 Use of amines and/or Mannich adducts in fuel and lubricant compositions for direct injection spark ignition engines BASF SE (DE) 2016-04-12 US disclosed
US-20130237466-A1 USE OF AMINES AND/OR MANNICH ADDUCTS IN FUEL AND LUBRICANT COMPOSITIONS FOR DIRECT INJECTION SPARK IGNITION ENGINES BASF SE (DE) 2013-09-12 US disclosed
US-8449630-B2 Use of amines and/or Mannich adducts in fuel and lubricant compositions for direct injection spark ignition engines BASF SE (DE) 2013-05-28 US disclosed
EP-1570031-B1 USE OF AMINES AND/OR MANNICH ADDUCTS IN FUEL AND LUBRICANT COMPOSITIONS FOR DIRECT INJECTION SPARK IGNITION ENGINES BASF SE (DE) 2012-03-21 EP disclosed
US-20060070293-A1 Use of amines and/or mannich adducts in fuel and lubricant compositions for direct injection spark ignition engines BASF SE (DE) 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287400-A1 NEW GASOLINE ADDITIVE PACKAGES NDUFS4, NDUFA10, COXFA4 SIGMAR1 742/4885HRH4 2360/4885HRH3 3417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.