Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27982509 | 0.77 | P2RX7 (0.42) | PLCG1KDM4ENPC1ALDH1A1GAA | |
| SCHEMBL14503016 | 0.77 | RIPK1 (0.40) | SMN1; SMN2KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL164726 | 0.75 | ALDH1A1 (0.41) | ANO1SMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL9284100 | 0.75 | KDM4E (0.51) | SMN1; SMN2KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL929825 | 0.74 | PLCG1 (0.45) | PLCG1SMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL9257568 | 0.74 | ALDH1A1 (0.39) | SMN1; SMN2KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL11502138 | 0.71 | MYC (0.37) | PLCG1KDM4EALDH1A1RAB9ANPSR1 | |
| SCHEMBL31426964 | 0.68 | ANO1 (0.40) | ANO1SMN1; SMN2HPGDRIPK1POLB | |
| SCHEMBL30853475 | 0.68 | SMN1; SMN2 (0.48) | ANO1SMN1; SMN2KDM4ENPC1ALDH1A1 | |
| SCHEMBL4605525 | 0.68 | SMN1; SMN2 (0.48) | ANO1SMN1; SMN2KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680955-B1 | PROCESS FOR PRODUCING N-tert-BUTYL-2-PYRAZINECARBOXAMIDE AND N-tert-BUTYL-2-PIPERAZINECARBOXAMIDE | KOEI CHEMICAL CO (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-5922873-A | Process for preparing N-tert-butyl-2-pyrazinecarboxamide and N-tert-butyl-2-piperazinecarboxamide | KOEI CHEMICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| US-5734055-A | Process for preparing N-tert-butyl-2-pyrazinecarboxamide and N-tert-butyl-2-piperazinecarboxamide | KOEI CHEMICAL CO. LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0680955-A1 | PROCESS FOR PRODUCING N-tert-BUTYL-2-PYRAZINECARBOXAMIDE AND N-tert-BUTYL-2-PIPERAZINECARBOXAMIDE | KOEI CHEMICAL CO., LTD. (JP) | 1995-11-08 | — | — | EP | disclosed |