Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503016 | 0.85 | RIPK1 (0.40) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL9284100 | 0.83 | KDM4E (0.51) | ALDH1A1SMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL164726 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL11877003 | 0.79 | MAPT (0.39) | ALDH1A1LMNAKDM4EPRKCIMAPT | |
| SCHEMBL2492969 | 0.77 | TSHR (0.48) | ALDH1A1LMNASMN1; SMN2KDM4EPRKCI | |
| SCHEMBL22190220 | 0.76 | HDAC1 (0.41) | ALDH1A1KDM4EPRKCIMAPT | |
| SCHEMBL7576218 | 0.74 | PLCG1 (0.42) | ALDH1A1LMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL13544700 | 0.73 | ADORA3 (0.41) | ALDH1A1LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL8052528 | 0.72 | KMT2A (0.47) | ALDH1A1SMN1; SMN2KDM4ENPC1TP53 | |
| SCHEMBL4605525 | 0.71 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2KDM4ENPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7291947-A | — | — | None | — | — | JP | disclosed |
| JP-H07291947-A | PRODUCTION OF N-T-BUTYL-2,3-PIRAZINEDICARBOXAMIDE AND PRODUCTION THEREOF | KOEI CHEM CO LTD | 1995-11-07 | — | — | JP | disclosed |