Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850407 | 0.99 | AGTR1 (0.53) | HTTALDH1A1TSHRAGTR1AGTR2 | |
| SCHEMBL27783641 | 0.99 | AGTR1 (0.53) | HTTALDH1A1TSHRAGTR1AGTR2 | |
| SCHEMBL23043613 | 0.80 | ALDH1A1 (0.52) | HTTALDH1A1TSHRLMNATP53 | |
| SCHEMBL17933567 | 0.76 | MAPT (0.72) | TSHRGLAKDM4ELMNATLR7 | |
| SCHEMBL2948522 | 0.75 | TLR7 (0.53) | TSHRAGTR1AGTR2GLAKDM4E | |
| SCHEMBL6142135 | 0.75 | MEN1 (0.66) | TSHRAGTR1AGTR2GLAKDM4E | |
| SCHEMBL11395129 | 0.75 | MAPT (0.75) | TSHRAGTR1AGTR2GLAKDM4E | |
| SCHEMBL1628969 | 0.74 | SMN1; SMN2 (0.42) | TSHRLMNATP53SMN1; SMN2GAA | |
| SCHEMBL10325213 | 0.74 | MEN1 (0.64) | AGTR1AGTR2GLAKDM4ELMNA | |
| SCHEMBL2361056 | 0.74 | TP53 (0.69) | HTTGLALMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013474-A1 | Process for the preparation of UV filter substances | MERCK PATENT GESELLSCHAFT | 2002-01-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013474-A1 | Process for the preparation of UV filter substances | AOX1, CYP1A1, AOC2 | HTT 3641/4885ALDH1A1 19/4885TSHR 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.